We see that the egoic life basically does not respect the autopoietic nature of the soul; it tends to make the open, living system that is the soul in a closed and isolated one, more like a machine. The difference between the egoic and the essential life is not absolute, for the soul cannot become completely a machine. She is inherently an open and dynamic system, and hence rigid ego structuring only limits this openness and constrains her dynamism; it cannot completely eliminate them (559)
This is a little off from the biological Autopoietic theory, but it is very useful. Autopoiesis is not only “open” but it is also “closed”. The theory speaks of autopoietic systems as being “organizationally closed”, but “structurally open”. As long as the changes do not (radically) change the organization of the system it remains autopoietic and in that way “closed”. What Almaas is describing is the structural closure of the system, in a way, that which could starve it. The calcifications of the ego would close off it’s dynamic of exchange. It would begin to suffer entropy at a rapid rate.